Introduction: A Small Molecule with Vast Influence S-adenosylmethionine (SAM-e) is a small molecule with vast biological reach. As the universal methyl donor, it influences DNA,…
Red ThreadBalance is the essence of life. The endocannabinoid system (ECS) is a master regulator of stress, mood, pain, and immunity — and epigenetics decides…
Red Thread The human soul, as Erich Fromm saw it, is not a metaphysical mystery but the dialectical essence of being: love and fear,…
The Brain’s Epigenetic Story Guiding Question How does the brain store experiences as epigenetic marks—shaping memory, emotion, and vulnerability to disease? The Red Thread The…
The Heart’s Epigenetic Story Guiding Question How does the heart remember love, stress, and lifestyle through its epigenome? The Red Thread The heart is not…
Epigenetics: The Language of Genes Guiding Question If DNA is the alphabet, what grammar lets cells turn the same letters into different meanings—health or disease,…
Why do arteries remember every stress and every toxin—so that inflammation outlasts the exposure itself? Case Vignette – Robert, 62 Robert, a 62-year-old accountant, comes…
The Big Picture: Judgment, Choice, and Renewal When Michelangelo painted The Last Judgment on the wall of the Sistine Chapel (1534–1541), he did not just…
Epigenetics of COPD – When the Environment Rewrites the Lung Epigenome Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide.…
Epigenetics of Liver Diseases and Cholestasis: How Environment and Metabolism Rewrite Hepatic Health
Between metabolic stress, toxic exposure, and regulatory misprogramming Introduction: The liver as an epigenetic target organ The liver is one of the most epigenetically…